Prevalence of Helicobacter pylori Infection in Western Romania
Ioan Sporea1, Alina
Popescu1, Mark van Blankenstein3, Roxana Sirli1, Mircea Focsa2,
1) Dept. of Gastroenterology.
2) Dept. of Medical Informatics, University of Medicine and
Pharmacy, Timisoara. 3) Dept of Gastroenterology, Academisch
Ziekenhuis Rotterdam, Holland
The aim of
this study was to evaluate the prevalence of Helicobacter Pylori
(HP) infection in a representative group of workers in Timis
methods: Our study population consisted of 960 employees:
206 F (21.46%) and 754 M (78.54%), mean age 36.8+7.6 years (range
18-60 years) from a company in Timisoara, in whom we assessed
IgG anti HP antibodies. We standardised our study population
for the age and gender distribution of the population in Timis
County and we excluded under 18 and over 60 years age groups
which were underrepresented.
Antibodies were found in 691individuals (71.9%). In females,
the prevalence of HP infection was 63.1% (130/206) and in males
74.4% (561/754). In the age group 18-30 years - 65.3%, males-67%,
females-56.8% (p=0.240); in group 31 - 40 years - 71.6%, males-74.4%,
females-63.5% (p=0.025); in group 41 - 50 years - 75%, males
- 78%, females-62.5% (p=0.026); and in group 51 - 60 years -
88.7%, males-87.2%, females - 100% (p=0.35). After standardisation
for age and gender, the prevalence of HP infection in the adult
population was 68.5%; in females - 63.8%, in males - 73.5% (p=0.08).
In a population sample significant for Timis County, the prevalence
of HP infection is 68.5% in the adult population, slightly higher
in males than in females (74.4% vs 63.1) (p=0.08), and it has
a tendency to increase with age.
– prevalence – epidemiology