Postprandial Walking but not Consumption of Alcoholic Digestifs or Espresso Accelerates Gastric Emptying in Healthy Volunteers

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Andreas Franke, Hermann Harder, Anna K. Orth, Sabine Zitzmann, Manfred V. Singer

Department of Medicine II (Gastroenterology, Hepatology and Infectious Diseases), University Hospital of Heidelberg at Mannheim, Mannheim, Germany


Background: Postprandial consumption of alcoholic beverages with high ethanol concentration (so-called digestifs) is a widespread custom to alleviate dyspeptic symptoms after comprehensive meals. Alcoholic beverages preprandially ingested inhibit gastric emptying rate of solid meals. However, the effect of a postprandial intake has never been studied in a controlled manner.

Methods: In 10 healthy male subjects gastric emptying was repeatedly studied by ultrasonography after the intake of a 576 kcal meal. Immediately after the meal subjects received in a randomized order 40 ml of the following liquids: brandy, herb flavored liqueur, Williams pear brandy, aquavit (each 40 % (v/v) ethanol concentration), espresso, water, 40% (v/v) ethanol and 70% (w/v) glucose. Postprandial satiety, fullness and bloating were determined on a visual analogue scale every 10 minutes. On another occasion subjects received 40 ml of water and walked afterwards slowly (4 km/h) on a treadmill.

Results: Gastric half emptying time (t 1/2) of the meal with water was 1235 min, while with brandy (1199 min), herb flavored liqueur (12310 min), aquavit (1259 min), Williams pear brandy (1266 min) or espresso (1259 min) t(1/2) it was not significantly different. Postprandial walking accelerated t(1/2) significantly (1075 min, p=0.02). Dyspeptic symptoms were unchanged. Blood ethanol concentrations were under the level of detection (< 5 mg/dl).

Conclusions: Postprandial consumption of alcoholic digestifs did not affect gastric emptying rate of a solid meal nor postprandial dyspeptic complaints. However, postprandial walking accelerated gastric emptying of the meal but this had no effect on dyspeptic symptoms.

Key words
Gastric emptying - ultrasound - alcohol - coffee - walking