Esophageal Motility Disorders in Diabetes Mellitus: a Manometric Study

Corina Moldovan1, Dan L. Dumitrascu2, Carmen Cruciat2, Ofelia Anton2, Monica Marin2, Diana Dumitrascu2, Brândusa Truta2, Doru Dejica2


Aim. The investigation of the esophageal motility in diabetes mellitus.

. 31 patients were investigated by water-perfused stationary esophageal manometry. Data were correlated with symptoms and with endoscopic and roentgenologic findings.

. 65% of the patients suffered from esophageal symptoms. They showed manometric abnormalities in 71% of cases. Symptoms suggesting gastroesophageal reflux disease (GERD) were associated with manometric findings corresponding to this disorder and with the presence of esophagitis at endoscopy. Simultaneous contractions at manometry correlated with the roentgenologic appearance of tertiary contractions, even in the absence of symptoms. Symptoms and manometric abnormalities did not correlate with RR variability on electrocardiography.

. Patients with diabetes mellitus frequently have esophageal symptoms and manometric abnormalities. Patterns consistent with GERD are most frequent, while patterns of hypercontractility were less frequently encountered.

Key words

Autonomic neuropathy - diabetes mellitus - esophagus- manometry - motility