Motility Disorders in Diabetes Mellitus: a Manometric Study
Corina Moldovan1, Dan L. Dumitrascu2, Carmen Cruciat2, Ofelia
Anton2, Monica Marin2, Diana Dumitrascu2, Brândusa Truta2,
Aim. The investigation of the esophageal motility
in diabetes mellitus.
Material-methods. 31 patients were investigated by
water-perfused stationary esophageal manometry. Data were correlated
with symptoms and with endoscopic and roentgenologic findings.
Results. 65% of the patients suffered from esophageal
symptoms. They showed manometric abnormalities in 71% of cases.
Symptoms suggesting gastroesophageal reflux disease (GERD) were
associated with manometric findings corresponding to this disorder
and with the presence of esophagitis at endoscopy. Simultaneous
contractions at manometry correlated with the roentgenologic
appearance of tertiary contractions, even in the absence of
symptoms. Symptoms and manometric abnormalities did not correlate
with RR variability on electrocardiography.
Conclusions. Patients with diabetes mellitus frequently
have esophageal symptoms and manometric abnormalities. Patterns
consistent with GERD are most frequent, while patterns of hypercontractility
were less frequently encountered.
Autonomic neuropathy - diabetes mellitus - esophagus- manometry