pylori Colonization in Dental Plaque and Gastric Infection
Mohtatam Nasrolahei1, Iraj
Maleki2, Omid Emadian3
1) Microbiology and Immunology
Department, Sari Medical School. 2) Department of Gastroenterology.
3) Department of Pathology, Emmam Khomeini Hospital, Sari, Iran
With regard to the presence of Helicobacter pylori ( H.pylori
) in dental plaque and its association with gastric infection,
data from the literature are controversial. The aim of this
study was to determine the prevalence of H.pylori in dental
plaque of dyspeptic patients who underwent upper gastrointestinal
endoscopy and to investigate its relationship to gastric infection.
In a cross sectional study, over one year ( February 2002-February
2003) samples were taken with separate sterile curretes from
tooth surfaces of molars, premolars and incisors of 180 consecutive
dyspeptic patients referred to the Endoscopy Department of Emmam
Khomeini Hospital. Dental plaque samples were subjected to the
rapid urease test, Giemsa staining , PCR test and culture for
identification of H.pylori. During endoscopy, six biopsies were
taken from the gastric antrum and corpus and histological examination,
Giemsa stainings, Rapid Urease test and culture were performed.
Patients were defined as infected when both rapid urease test
and Giemsa stain, or when cultures were positive for H.pylori.
Informations concerning oral hygiene protocol were recorded.
For data analysis , the chi square test was used and P<0.05
was defined statistically significant.
Our data proved the presence of H. pylori in dental plaque of
infected and uninfected patients. There was no significant association
between H. pylori colonization in dental plaque and gastric
infection. In this study, oral hygiene (the frequency of dental
visits and teeth cleaning) did not have a significant influence
on the presence of H. pylori in dental plaque.
Dental plaque is the reservoir of H.pylori with no relationship
to gastric infection.
Dental plaque - gastric
infection - gastrointestinal endoscopy - Helicobacter pylori