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CASE REPORT

Self-Administered Home Series Fecal “Minitransplants” for Recurrent Clostridium difficile Infection on a Rectal Remnant

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Daniel Popa¹,², Mihaela Laszlo³, Lidia Ciobanu³,⁴, Elena Ucenic², Manuela Mihalache¹, Oliviu Pascu³,⁴

1) Lucian Blaga University,
2) Polisano Clinic, Sibiu;
3) Department of Gastroenterology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology;
4) 3rd Medical Clinic, Iuliu Hatieganu University of Medicine and Pharmacy,
Cluj-Napoca, Romania

DOI: http://dx.doi.org/10.15403/jgld.2014.1121.244.clo

ABSTRACT
A fecal microbiota transplant has proved to be an extremely effective method for patients with recurrent infections with Clostridium difficile. We present the case of a 65-year-old female patient with multiple Clostridium difficile infection (CDI) relapses on the rectal remnant, post-colectomy for a CDI-related toxic megacolon. The patient also evidenced associated symptomatic Clostridium difficile vaginal infection. She was successfully treated with serial fecal “minitransplants” (self-administered at home) and metronidazole ovules.

Key words: Clostridium difficile infection – fecal microbiota transplant – rectal remnant – post-colectomy.
Abbreviations: GI: gastrointestinal; MRI: magnetic resonance imaging; CDI: Clostridium difficile infection; FMT: fecal microbiota transplant.