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Images of the Issue
Unexpected appearance of esophageal spastic activity after pneumatic dilatation in a patient with type II achalasia
A. Ioannou, D. Mandolesi, F. Bazzoli, F. Torresan

Endoscopic retrieval of a proximally migrated biliary plastic stent using direct per-oral cholangioscopy
R. Maselli, E. Troncone, A. Fugazza, F. Auriemma, A. Anderloni, A. Cappello, A. Repici

CT-scan fat halo sign in a patient with abdominal mass and constipation
G. Marasco, R.M. Zagari, F. Bazzoli

Original Papers
Sequential therapy for first-line Helicobacter pylori eradication: 10- or 14-day regimen?
A. Zullo, G. Fiorini, G. Scaccianoce, P. Portincasa, V. De Francesco, R. Vassallo, F. Urban, F. Monica, G. Mogavero, A. Amato, D. Vaira

Capsule endoscopy in the management of refractory coeliac disease
S. Chetcuti Zammit, D.S. Sanders, S.S. Cross, R. Sidhu

The “DICA” endoscopic classification for diverticular disease of the colon shows a significant interobserver agreement among community endoscopists
A. Tursi, G. Brandimarte, F. di Mario, G. Nardone, C. Scarpignato, M. Picchio, W. Elisei, DICA Italian Group

Sense of coherence in people with and without inflammatory bowel diseases – is there a difference?
T. Naftali, A. Eindor-Abarbanel, N. Ruhimovich, A. Bar-Gil Shitrit, F. Sklerovsky-Benjaminov, I. Laish, S. Matalon, H. Shirin, Y. Milgrom, T. Ziv-Baran, E. Broide

Training and assessment in flexible sigmoidoscopy: using a novel direct observation of procedural skills (DOPS) assessment tool
K. Siau, J. Crossley, P. Dunckley, G. Johnson, A. Haycock, J.T. Anderson, M. Iacucci, M. Feeney, on behalf of the Joint Advisory Group on Gastrointestinal Endoscopy (JAG)

Efficacy of naldemedine for the treatment of opioid-induced constipation: a meta-analysis
M. Esmadi, D. Ahmad, A. Hewlett

Increased prevalence of autonomic dysfunction due to postural orthostatic tachycardia syndrome in patients with eosinophilic gastrointestinal disorders
K.Z. Huang, E.S. Dellon

Cirrhosis risk score of the donor organ predicts early fibrosis progression after liver transplantation
A. Zimmermann, F. Darstein, M. Hoppe-Lotichius, G. Toenges, A. Lautem, F. Abel, A. Schad, J. Mittler, J. Vollmar, D. Grimm, H. Lang, P.R. Galle, T. Zimmermann, D. Schuppan

Predictive factors for hepatocellular carcinoma occurrence or recurrence after direct-acting antiviral agents in patients with chronic hepatitis C
Y. Yoshimasu, Y. Furuichi, Y. Kasai, H. Takeuchi, K. Sugimoto, I. Nakamura, T. Itoi

Short sleep duration is a risk of incident nonalcoholic fatty liver disease: a population-based longitudinal study
T. Okamura, Y. Hashimoto, M. Hamaguchi, A. Obora, T. Kojima, M. Fukui

Effects of implementation of a national fast track clinical pathway for hepatocellular carcinoma in western Denmark
G.E. Villadsen, K. Simonsen, P. Ott, H. Vilstrup, H. Grønbæk

Direct peroral cholangioscopy in the management of difficult biliary stones: a new tool to confirm common bile duct clearance. Results of a preliminary study
A. Anderloni, F. Auriemma, A. Fugazza, E. Troncone, L. Maia, R. Maselli, S. Carrara, F. D’Amico, P.J. Belletrutti, A. Repici

Systematic Review and Meta-Analysis
Prevalence of gluten-related disorders in Asia-Pacific region: a systematic review
S. Ashtari, M.A. Pourhoseingholi, K. Rostami, H.A. Aghdaei, M. Rostami-Nejad, L. Busani, M.R. Tavirani, M.R. Zali

Anterior versus posterior myotomy during POEM for the treatment of achalasia: systematic review and meta-analysis of randomized clinical trials
E. Rodriguez de Santiago, N. Mohammed, A. Manolakis, Y. Shimamura, M. Onimaru, H. Inoue

Case Reports
Ulcerative colitis associated with gastric heterotopia in the rectum: a case report
R.G. Antemie, A.P. Apostu, L. Rogojan, R.I. Chira

Liver damage in a patient with Gaucher’s disease type I and alpha-1 antitrypsin deficiency: a potential epigenetic effect?
M.L. Alves Pedroso, C.N. Didoné Filho, V. Radunz, J.A. de Barros

Beyond palliation: using EUS-guided choledochoduodenostomy with a lumen-apposing metal stent as a bridge to surgery. A case series
C. Fabbri, A. Fugazza, C. Binda, A. Zerbi, E. Jovine, V. Cennamo, A. Repici, A. Anderloni

Letters
A novel hybrid first-line therapy for H. pylori eradication: results of a pilot study
V. De Francesco

Ultrasonographic assessment of Crohn’s disease patients: can be easier and more affordable for clinical practice?
A. Les, A. Dimitriu, R. Costache, L. Gheorghe, C. Gheorghe

Reply
B. Dorottya Lovasz, A. Ilias, L. Gonczi, P.L. Lakatos

A difficult path in the management of irritable bowel syndrome: from general recommendations to clinical reality
L. Nedelcu

Reply
M. Radu, A. Băban, D.L. Dumitrascu