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Guidelines for Authors

Guidance for Authors on the Preparation and Submission of Manuscripts to the Journal of Gastrointestinal and Liver Diseases*

Scope
The Journal of Gastrointestinal and Liver Diseases (JGLD) publishes papers reporting original clinical and scientific human research, which are of a high standard and which contribute to the advancement of knowledge in the field
of gastroenterology and hepatology. The field comprises prevention, diagnosis and management of gastrointestinal and hepatobiliary disorders, as well as related molecular genetics, pathophysiology, and epidemiology. We do not publish animal experimental studies. Known personalities with expertise and published studies in a specific field are invited to write reviews and editorials in our journal. Un-invited reviews will also be accepted if written by experts with publications in the field.

Due to limited space, we do not accept papers related to pediatric pathology or to surgical techniques. Case reports will be accepted if of great interest and well investigated. Technical Reports and Clinical Imaging chapters should include new or improved techniques and devices used in clinical research or in the practice of gastroenterology and hepatology. Publication of clinical trials will be considered only for those registered in a public trials registry. Letters to the Editor, especially those mentioning an opinion on an article previously published, or expressing a new finding are welcome. Letters are selected for their importance and not all letters submitted will be published.
Submission and procession of manuscripts is free of charge for authors.

The journal is published quarterly and papers are accepted for publication in English language. Manuscripts that do not conform to standard English style, usage or grammar are returned to the authors for modification prior to scientific review.

The website address of the JGLD is http://www.jgld.ro.

Contact information for correspondence: Monica Acalovschi, MD, PhD, Editor J Gastrointestin Liver Dis, 3rd Medical Clinic, Str. Croitorilor 19-23, 400162, Cluj-Napoca, Romania, Tel: +40 264 433 427, Fax: +40 264 431 758. Email: editorjgld@gmail.com

Please consider before submission
A cover letter should accompany your submission. Please consider the following points and make the appropriate
declarations.
Redundant or duplicate publication*
We ask you to confirm that your paper has not been published in its current form or a substantially similar form (in print or electronically, including on a website), that it has not been accepted for publication by another journal, and that it is not under consideration by another publication.
The International Committee of Medical Journal Editors (ICMJE) has provided details regarding duplicate or redundant publications (http://www.icmje.org). In your cover letter to the editors, please mention any published work that concerns the same patients or subjects as the present paper. Manuscripts submitted might be checked with plagiarism detecting software. Papers published in duplicate will be retracted from the journal.
Conflicts of interest
Please state all possible conflicts of interest, including financial and other relationships. If you are sure that there is no conflict of interest, please state this also. The sources of funding should be acknowledged in your paper.
A form of Disclosure of Conflicts of Interest can be downloaded and completed electronically from www.icmje.org.
Permissions to reproduce published material
Please send us copies of permission to reproduce material (such as illustrations) from the copyright holder.
Patients᾿ consent forms
The protection of a patient’s right to privacy is essential. Please send copies of patients’ consent forms on which patients or other subjects of your experiments clearly grant permission for the publication of photographs or other material that might identify them.
Even if patient-identifying material is not included in your paper, all studies dealing with patients or normal volunteers (including case reports) need their written informed consent.
A statement must be included in the ‘Methods’ section of your paper.
Ethics Committee approval
You must state clearly in your submission in the Methods section that you conducted studies on human participants with the approval of the Hospital or University Ethics Committee.

Authorship
We ask all authors to sign the submission letter in order to confirm that they have read and approved the paper. We also ask all authors to confirm that they have met the criteria for authorship as established by the ICMJE, believe that the paper represents honest work, and are able to verify the validity of the results reported. The Editorial Committee will accept two authors as „first authors” of the same paper only in exceptional situations if contributions in the research prove to be similar.
No more than 6 authors are accepted for Case Reports or Images of the issue. Only one author should be the corresponding author. A list of authors᾿ contributions must accompany the manuscript.
The editors will handle cases of suspected misconduct or disputed authorship according to the COPE flowcharts.

Copyright assignment
Papers are accepted for publication on the understanding that exclusive copyright in the paper is assigned to the
Publisher. Authors are asked to sign a copyright assignment form after acceptance of their papers (www.jgld.ro). They may use material from their paper in other works published by themselves. Signature of the copyright form is a condition of publication and papers will not be passed to the publisher unless a signed form has been received.

Submission

The journal only accepts electronic submission of manuscripts in Word format (see Online manuscript submission). A Word copy of the full manuscript and a PDF copy of the manuscript including the tables and figures should be additionaly submitted.
The word count accepted is up to 3,500 words for original articles, 4,500 words for review articles, 1,500 for Editorials, Case reports and Clinical Imaging manuscripts, 400-500 for Letters, 300 for Images of the issue and 2,000 for Educational materials.
Double spacing should be used throughout the manuscript, which should include the following sections, each starting on a separate page: title page, abstract and key words, text, acknowledgements, references, individual tables and legend for figures. Pages should be numbered consecutively, beginning with the title page.

Presentation of papers

Title page
The title page should carry the full title of the paper and a short title to be used as a ‘running head’ (which should comprise up to 45 characters). The first name, middle initial and last name of each author should appear. If the work is to be attributed to a department or institution, its full name should be included.
Any disclaimers should appear on the title page, as should the name and address of the author responsible for correspondence concerning the manuscript (the author should mention if he does not want his e-mail address to be published). A word count for the text only (excluding abstract, acknowledgement, figure legends, and references) allows editors and reviewers to assess whether the information contained in the paper warrants the amount of space devoted to it, and whether the submitted manuscript fits within the journal’s word limits. A separate word count for the Abstract is also useful.
Finally, the title page should include the sources of any support for the work in the form of grants, equipment, drugs,
or any combination of these.

Abstract
The second page should carry a structured abstract for original papers of no more than 250 words. Do not use
abbreviations, footnotes, or references.
Background & Aims. Describe the importance of the study and the precise research objective(s) or study question(s).
Methods. Methods should include information on the following aspects when applicable:
Design – describe the basic study design, e.g. randomized controlled trial, cross sectional study, cohort study, case series, survey etc;
Setting – specify whether the study was conducted in a primary or tertiary care setting, in an ambulatory care clinic
or hospital, in the general community etc;
Participants – indicate the number of study subjects and how they were selected, recruited, and assigned to the intervention;
Intervention – report the method of administration and duration of the intervention.
Results. Provide the main outcomes of the study, including confidence intervals or p values.
Conclusion. State only conclusions that are directly supported by the evidence and the implications of your findings.

Key words
The abstract should be followed by a list of 3–10 key words or short phrases which will assist the cross-indexing of the article and which may be published. When possible, the terms used should be from the Medical Subject Headings list of Index Medicus (http://www.nlm.nih.gov/mesh/meshhome.html).

Text
Full papers of an original study should be divided into sections headed Introduction, Methods (including ethical and
statistical information), Results, Discussion and Conclusion.
Long articles may require subheadings within some sections (especially the Results and Discussion) to clarify their content.
Observational studies in epidemiology should be reported according to the STROBE checklists. Reports of clinical trials should adhere to the CONSORT statement. Systematic reviews should be organized according to PRISMA guidelines. Other types of articles, such as case reports, narrative reviews, and editorials, are likely to require other formats.
Outline statistical methods used. An expert in biomedical statistics could be invited to evaluate the statistical methods used in the paper. Identify drugs and chemicals used by generic name (if trade-marks are mentioned, manufactured name and city should be given).

Acknowledgements
Acknowledge only those who have made a substantial contribution to the study. Authors are responsible for obtaining written permission from people acknowledged by name in case readers infer their endorsement of data and conclusions.

References
References should be numbered consecutively in the order in which they first appear in the text. They should be assigned Arabic numerals, which should be given in brackets, e.g. [12]. References should include the names of all authors when six or fewer; when seven or more, list only the first three names and add et al. References should also include full title and source information. Journal names should be abbreviated as in Index Medicus (http://www.nlm.nih.gov/tsd/serials/terms_cond.html).
No more than 100 references will be accepted for reviews. For Images of the Issue, 5-6 references. Abbreviations of journals conform to those used in Index Medicus.
Please provide for all references, where available, the DOI citation numbers.

Articles
Jüngst C, Lammert F. Cholestatic liver disease. Dig Dis 2013; 31: 152-154. doi: 10.1159/000347210 Raman M, Ahmed I, Gillevet PM, et al. Fecal microbiome and volatile organic compound metabolome in obese humans with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 2013; 11: 868-875.e1-3. doi: 10.1016/j. cgh.2013.02.015

Books
Whitehead WE, Schuster MM. Gastrointestinal Disorders. Behavioral and Physiological Basis for Treatment. Orlando: Academic Press, 1985. Chapter in Book Tack J. Nausea and vomiting. In: Textbook of Clinical Gastroenterology and Hepatology, 2nd Edition. C. J. Hawkey, J. Bosch, J.E. Richter, G. Garcia-Tsao, Francis K. L. Chan (Eds.). Oxford: Wiley-Blackwell, 2012: 26-31
Avoid or keep as low as possible the use of abstracts as references. Personal communications and unpublished work
should not feature in the reference list but should appear in parentheses in the text. Unpublished work accepted for publication but not yet released should be included in the reference list with the words ‘in press’ in parentheses beside the name of the journal concerned. References must be verified by the author(s) against the original documents, although JGLD also checks the accuracy of the references.

Tables
Each table should be cited in the text.
Tables should be typed on a separate sheet in double spacing. Each table should be assigned a Roman numeral (e.g. Table III) and a brief title. Explanatory matter should be placed in footnotes. Explain in footnotes all non-standard abbreviations that are used in each table. Identify statistical measures of variations, such as standard deviation and standard error of the mean.

Illustrations
All graphs, photographs (on glossy paper), diagrams will be referred to as figures and should be numbered consecutively in the text in Arabic numerals. They will be submitted electronically as a separate electronic file, preferably named as “figure 1.tiff ”, figure 2.jpg” etc. Do not prepare too small images, as there is no effective way to increase the resolution of an image beyond its original size. Figures must be at least 150 dpi to ensure quality. If scanned, line art should be at a resolution of 800 dpi, and halftones and colour at 300 dpi. For vector images (graphs, carts), eps is the best format to be used.
If a figure has been published before, the original source must be acknowledged and written permission from the copyright holder for both print and electronic formats should be submitted with the material.
Figures may be reduced, cropped or deleted at the discretion of the Editor.
Figures that are submitted in color will be published with reproduction costs (20€ or 24 USD per figure). Send agreement to pay for color figures by email to editorjgld@gmail.com.

Legends for illustrations
Captions should be typed in double spacing, beginning on a separate page. Each one should have an Arabic numeral corresponding to the illustration to which it refers with a title above and explanatory notes below it. Do not embed image files or other objects in your Word document. Internal scales should be explained and staining methods and magnification for photomicrographs should be identified.

Units of measurement
Measurements of length, height, weight, and volume should be reported in metric units (meter, kilogram, or litre) or their decimal multiples. Temperatures should be given in degrees Celsius. Blood pressure should be given in mmHg.
All hematological and clinical chemistry measurements should be reported in the metric system in terms of the International System of Units (SI). Editors may request that alternative or non-SI units be added by the authors before publication.

Abbreviations and symbols
Use only standard abbreviations. Avoid abbreviations in the title and abstract. The full term for which an abbreviation stands should precede its first use in the text unless it is a standard unit of measurement.
A list of abbreviations in alphabetical order should be included when many abbreviations are used.

Pre-submission checklist
This list will be useful during the final checking of an article prior to sending it to the Journal’s Editor for review:
– one author designated as corresponding author: with e-mail address, full postal address, telephone and fax numbers;
– all necessary files uploaded;
– keywords, running head;
– all figures and tables (with title, description, foot-notes);
– references in the correct format for this Journal;
– all references mentioned in the reference list cited in the text, and vice versa;
– permission obtained for use of copyrighted material
After publication
A copy of the Journal will be supplied to the authors free of charge.

Online manuscript submission
The process is simple. Go to www.jgld.ro, click on Guidelines for authors and read the guidelines. Then, back on the home page of www.jgld.ro, go to Submit an article and click. The first time you use the system, you will register for an account. You will use your account log-in and password each time you return to the site, whether to make changes in your manuscript (edit) or check on the status on the left menu. In case you forget the password, you have the possibility to get a new one by using the button Forgot your password. You will receive an e-mail with the link where you can introduce a new password.
After you log on, click on Add new article and start to submit the manuscript – article type, title, authors, abstract, key words, article body, references, figures, tables, proposed reviewers and cover letter, in the required order. You should propose 3 or more reviewers. Reviewers should be personalities with many published papers in the field, from different cities and diverse countries, so that any possible conflict of interest be avoided. Your text and figures will be uploaded in a few minutes and you will first save the manuscript. Then you will see it again and check for corrections. Please insert a Word copy of the full manuscript and also the pdf including tables and figures in the “Article tables and Full manuscript” section. You click on Send to Editor and your manuscript will be submitted. Once in our system, the manuscript is assigned a tracking number and you will receive a confirmation letter. After sending, your manuscript will appear as under evaluation.
As soon as the reviewers’ comments are ready, you will receive a letter from the editor confirming acceptance, inviting you to revise your manuscript, or informing you that the manuscript cannot be accepted for publication. If you are invited to revise your manuscript you have the possibility to make the corrections and send the manuscript again. You should add a reply letter to the reviewers answering point by point their
comments.
If you encounter any problem when submitting your manuscript, please contact us: editorjgld@gmail.com
Peer-review procedure
The JGLD offers online submission, online thorough peer review, and immediate publication on acceptance. The journal is advised by an International Editorial Board and a local
Editorial Board.
The Editor-in-chief or one of the editors first reads the manuscripts received and decides upon their priority level: some are immediately sent to the reviewers, some are rejected without being sent for review and some are returned to authors with suggestions for improvement before submitting them to reviewers.
All the original papers are anonymously reviewed by two or three independent reviewers, of whom two are international personalities. The guidelines for reviewers are available on www.jgld.ro. In case no invited reviewer accepts to evaluate the manuscript in two months after submission, the manuscript will be returned to the authors. The reviewers are asked to evaluate the manuscript by applying the same standards as for the international journals. The reviewers send their comments to the Editor. The Editor will inform the authors about the suggestions made by the referee and ask them to answer the questions and make the required corrections.
The revised manuscript should be returned in no more than two months to the Editor. Revised manuscripts sent later will not be considered. When the Editor receives the corrected version with all changes marked, accompanied by a letter with a point-by-point reply to the reviewers’ comments, he sends those back to the same reviewers, who make the final recommendation for acceptance or rejection of the manuscript.
The Editor’s decision is final and will not be subject of further correspondence for manuscripts considered unsuitable for publication.
All accepted manuscripts are checked before printing by the English language Editor of the journal.

Open access
The abstract and text of the published articles will immediately be placed in PubMed. Thanks to the Open Access
policy of the Journal of Gastrointestinal and Liver Diseases, all original articles, reviews, editorials and case reports published in the journal are available online for all to read and use free of charge.

The Editorial Team
J Gastrointestin Liver Dis