Confocal Endomicroscopy for in vivo Microscopic Analysis of Upper Gastrointestinal Tract Premalignant and Malignant Lesions

Authors

  • Cristian Gheorghe Center of Gastroenterology and Hepatology, Fundeni Clinical Institute, Bucharest, Romania
  • Razvan Iacob Center of Gastroenterology and Hepatology, Fundeni Clinical Institute, Bucharest, Romania
  • Gabriel Becheanu Center of Gastroenterology and Hepatology, Fundeni Clinical Institute, Bucharest, Romania
  • Mona Dumbrava Center of Gastroenterology and Hepatology, Fundeni Clinical Institute, Bucharest, Romania J Gastrointestin Liver Dis March 2008 Vol.17 No 1, 95-100 Address for correspondence: Assoc. Prof. Dr. Cristian Gheorghe Center of

Keywords:

Confocal LASER endomicroscopy, malignant/premalignant digestive lesions

Abstract

Confocal LASER endomicroscopy (CLE) is a new endoscopic technique which allows subsurface in vivo microscopic analysis during ongoing endoscopy, using systemically or topically administered fluorescent agents. It allows targeted biopsies to be taken, potentially improving the diagnostic rate in certain gastrointestinal diseases. Worldwide experience with CLE for upper gastrointestinal malignant and premalignant lesions is still reduced. Potential clinical aplications are presented, including diagnosis of NERD, Barrett's esophagus, atrophic gatritis, gastric intestinal metaplasia and dysplasia, gastric adenomatous or hyperplastic polyps, gastric cancer.

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Published

2008-03-01

How to Cite

1.
Gheorghe C, Iacob R, Becheanu G, Dumbrava M. Confocal Endomicroscopy for in vivo Microscopic Analysis of Upper Gastrointestinal Tract Premalignant and Malignant Lesions. JGLD [Internet]. 2008 Mar. 1 [cited 2026 Jul. 16];17(1):95-100. Available from: https://www.jgld.ro/jgld/index.php/jgld/article/view/2008.1.16

Issue

Vol. 17 No. 1: March 2008

Section

Clinical imaging