Esophageal Xanthoma – Report of Two New Cases and Review of the Literature

Authors

  • Gabriel Becheanu Gastroenterology and Hepatology Department, Fundeni Clinical Institute, Bucharest, Romania
  • Mona Dumbrava Gastroenterology and Hepatology Department, Fundeni Clinical Institute, Bucharest, Romania
  • Tudor Arbanas Gastroenterology and Hepatology Department, Fundeni Clinical Institute, Bucharest, Romania
  • Mircea Diculescu Gastroenterology and Hepatology Department, Fundeni Clinical Institute, Bucharest, Romania
  • Nadia Hoyeau-Idrissi Pathology Department, Saint-Antoine Hospital, Paris, France
  • Jean-François Fléjou Pathology Department, Saint-Antoine Hospital, Paris, France

Keywords:

Esophagus, xanthoma, foamy macrophages, immunohistochemistry

Abstract

Background: Esophageal xanthoma is a very rare lesion which can be incidentally discovered during endoscopy. Only eleven cases have been reported, including ours.

Case reports: We present two new cases of esophageal xanthoma localized in the lower esophagus in a 56-year-old woman and a 62-year-old man. Endoscopically, esophageal xanthoma appears as yellowish granular spots or a slightly elevated lesion. Microscopically, it consists of fat accumulation in foamy histiocytes beneath the squamous epithelium.

Conclusions: The clinical and pathological importance of these lesions and what they mean in patients is discussed, along with a review of the literature.

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Published

2011-12-01

How to Cite

1.
Becheanu G, Dumbrava M, Arbanas T, Diculescu M, Hoyeau-Idrissi N, Fléjou J-F. Esophageal Xanthoma – Report of Two New Cases and Review of the Literature. JGLD [Internet]. 2011 Dec. 1 [cited 2026 Jul. 18];20(4):431-3. Available from: https://www.jgld.ro/jgld/index.php/jgld/article/view/2011.4.18

Issue

Vol. 20 No. 4: December 2011

Section

Case Reports