The Role of Psychotherapy in the Treatment of Patients with Non– alcoholic Fatty Liver Disease and Obstructive Sleep Apnea

Authors

  • Branka F Filipovic University of Belgrade, Faculty of Medicine, Belgrade; Dr. Dragiša Mišović– Dedinje Clinical and Hospital Center, Dept. of Gastroenterology, Belgrade, Serbia
  • Milan Latas University of Belgrade, Faculty of Medicine, Belgrade; Clinic for Psychiatry, Clinical Center of Serbia, Belgrade, Serbia
  • Stanimir Kiurski Dr. Dragiša Mišović– Dedinje Clinical and Hospital Center, Dept. of Gastroenterology, Belgrade, Serbia
  • Dezbal Al Kiswani Dr. Dragiša Mišović– Dedinje Clinical and Hospital Center, Dept. of Gastroenterology, Belgrade, Serbia
  • Natasa Filipovic Dr. Dragiša Mišović– Dedinje Clinical and Hospital Center, Dept. of Gastroenterology, Belgrade, Serbia
  • Marija Marjanovic-Haljilji Dr. Dragiša Mišović– Dedinje Clinical and Hospital Center, Dept. of Gastroenterology, Belgrade, Serbia
  • Darko Laketic University of Belgrade, Faculty of Medicine, Belgrade; Niko Miljanić Institute of Anatomy, Belgrade, Serbia
  • Milan Aksic University of Belgrade, Faculty of Medicine, Belgrade; Niko Miljanić Institute of Anatomy, Belgrade, Serbia
  • Branka Markovic University of Belgrade, Faculty for Sports and Physical Education, Belgrade, Serbia
  • Suncica Kapor Dr. Dragiša Mišović– Dedinje Clinical and Hospital Center, Dept. of Haematology, Belgrade, Serbia
  • Slobodan Kapor University of Belgrade, Faculty of Medicine, Belgrade; Niko Miljanić Institute of Anatomy, Belgrade, Serbia
  • Olivera Markovic University of Belgrade, Faculty of Medicine, Belgrade; Bezanijska Kosa Clinical and Hospital Center, Bezanijska s/n, Belgrade, Serbia
  • Ana Starcevic University of Belgrade, Faculty of Medicine, Belgrade; Niko Miljanić Institute of Anatomy, Belgrade, Serbia

DOI:

https://doi.org/10.15403/jgld-3758

Keywords:

non-alcoholic fatty liver disease, sleep apnea, obesity, body mass index, psychotherapy

Abstract

Background and Aims: Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease with extensive multi- organ involvement, whose extra-hepatic manifestations include diabetes mellitus type 2, cardiovascular disease, obstructive sleep apnea (OSA), chronic kidney disease, and polycystic ovary syndrome. Our hypothesis was that there was a strong psychological component in NAFLD and OSA suffering patients and that psychotherapy would be helpful in the treatment of the mentioned diseases.

Methods: Of 144 initially selected patients (with NAFLD, obesity and OSA), 32 patients agreed to undergo psychotherapy, and 31 therapy-naive NAFLD and OSA patients agreed to participate as controls.

Results: Psychological evaluation revealed that self-esteem rose significantly after one-year psychotherapy (p=0.005). Body mass index (BMI) was significantly lower after psychotherapy, followed by the changes in laboratory results. Binomial logistic regression revealed that the reduction of BMI in high probability led to self-esteem improvement (p=0.03).

Conclusions: Psychotherapy was an efficient supporting method in the treatment of patients with NAFLD, obesity and OSA. It raised self-esteem and stimulated the motivation for further treatment of obesity, as one of the important factors for NAFLD and OSA. Still, it is advisable to use psychotherapy in combination with other clinical methods of treatment.

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Published

2021-12-21

How to Cite

1.
Filipovic BF, Latas M, Kiurski S, Al Kiswani D, Filipovic N, Marjanovic-Haljilji M, Laketic D, Aksic M, Markovic B, Kapor S, Kapor S, Markovic O, Starcevic A. The Role of Psychotherapy in the Treatment of Patients with Non– alcoholic Fatty Liver Disease and Obstructive Sleep Apnea. JGLD [Internet]. 2021 Dec. 21 [cited 2026 Jul. 16];30(4):477-84. Available from: https://www.jgld.ro/jgld/index.php/jgld/article/view/3758

Issue

Vol. 30 No. 4: December 2021

Section

Original Article